shingles vaccine ingredients cdc

Thank you for taking the time to confirm your preferences. Severe allergic reactions following vaccination are rare, but can be life threatening. A single dose after reconstitution is 0.5 mL. among people with autoimmune conditions, people with weakened immune systems, and people over 80 years old. About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling. Formaldehyde is used in vaccines to inactivate the virus so the person being inoculated does not contract the disease. Recommendations of the Advisory Committee on Immunization Practices for Use of Herpes Zoster Vaccines, 2018. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. 2021), sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, and polysorbate 20 (Tween20), baculovirus and Spodoptera frugiperda cell proteins, baculovirus and cellular DNA, Triton X-100, Influenza Vaccine,Live, Intranasal (Quadrivalent, Types A and Types B), FluMist Quadrivalent Package Insert (Aug. 2021), specific pathogen-free (SPF) eggs, stabilizing buffer, monosodium glutamate, hydrolyzed porcine gelatin, arginine, sucrose, dibasic potassium phosphate, monobasic potassium phosphate, ovalbumin, gentamicin sulfate, ethylenediaminetetraacetic acid (EDTA), Influenza Virus Vaccine (Quadrivalent, Types A and Types B), Manufacturer: Glaxosmithkline Biologicals, Fluarix Quadrivalent Package Insert (2021), octoxynol-10 (TRITON X-100), tocopheryl hydrogen succinate, polysorbate 80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, sodium deoxycholate, Fluzone High-Dose Quadrivalent Package Insert (July 2021), Fluzone Quadrivalent Package Insert (2021), Fluzone Intradermal Quadrivalent Package Insert (May 10, 2016), Fluzone Quadrivalent Southern Hemisphere Package Insert (2021), Fluzone High-Dose Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution , octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Intradermal Quadrivalent: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton 17 X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone Quadrivalent Southern Hemisphere: embryonated chicken eggs, formaldehyde, linear sucrose density gradient solution, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, Fluzone High-Dose Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, gelatin, Fluzone Quadrivalent: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Intradermal Quadrivalent: sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Fluzone Quadrivalent Southern Hemisphere: thimerosal, sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, octylphenol ethoxylate, Flulaval Quadrivalent Package Insert (2021), phosphate-buffered saline solution, ovalbumin, formaldehyde, sodium deoxycholate, -tocopheryl hydrogen succinate, polysorbate 80, Japanese Encephalitis Virus Vaccine, Inactivated, Adsorbed, Vero cells, protamine sulfate, sucrose density gradient, formaldehyde, aluminum hydroxide, formaldehyde, bovine serum albumin, host cell DNA, sodium metabisulphite, host cell protein, protamine sulfate, 23. Even if you have side effects from the first dose, it is important to get the second dose to build strong protection against shingles. Shingrix provides strong protection against shingles and long-term pain from the disease. CDC recommends Shingrix as the preferred vaccine, over Zostavax, to prevent shingles and the complications from the disease. In addition to the rash, shingles can cause fever, headache, chills, or upset stomach. ], sodium chloride, lipids ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 2-(polyethylene glycol 2000)-N,N-ditetradecylacetamide, 1,2-distearoyl-sn-glycero-3-phosphocholine, cholesterol), potassium chloride, monobasic potassium phosphate, dibasic sodium phosphate dihydrate, sucrose, Vero cells (African Green Monkey kidney), stabilizer solution, sodium chloride, essential amino acids (including L-phenylalanine), non-essential amino acids, L-arginine hydrochloride, sucrose, D-trehalose dihydrate, D-sorbitol, trometamol, urea, aluminum phosphate, isotonic sodium chloride solution, formalin, tryptic digest of casein, cystine, maltose, uracil, inorganic salts, vitamins, 8. Common side effects, such as soreness and redness at the injection site, are usually mild to moderate in intensity and resolve quickly on their own. Chicago, Illinois 60654 USA, Natalie Leppard People who are moderately or severely ill should usually wait until they recover before getting recombinant shingles vaccine. glycerin, asparagine, citric acid, potassium phosphate, magnesium sulfate, iron ammonium citrate Vaccine Ingredients: (in addition to the virus strain (s) being vaccinated against) lactose, sterile water BCG Live Manufacturer: Organon Teknika Corp. Tice BCG Package Insert (Feb. 2009) Growth Mediums and Process Ingredients: Shingrix is administered in two doses, usually two to six months apart. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital. Symptoms usually go away on their own in 2 to 3 days. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. CDC twenty four seven. Safety of zoster vaccine in adults from a large managed-care cohort: A Vaccine Safety Datalink study. Rarely, shingles can lead to complications such as pneumonia, hearing problems, blindness, brain inflammation (encephalitis), or death. Tell your patients to contact their health insurance providers ahead of time to see if they will cover the vaccine. MMR & Varicella (measles, mumps, rubella, & chickenpox), 33. Shingrix vs. Zostavax Afluria Quadrivalent Southern Hemisphere: allantoic fluid of embryonated chicken eggs, sucrose density gradient, beta-propiolactone, sodium taurodeoxycholate, phosphate buffered isotonic solution. 68.2% among adult autologous hematopoietic cell transplant recipients. The virus that causes shingles is called varicella-zoster virus. Safety, tolerability, and immunogenicity of zoster vaccine in subjects with a history of herpes zoster. Otherwise, discard it. ZOSTAVAX contains a weakened chickenpox virus (varicella-zoster virus). The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Zostavax [PDF - 13 Pages] The FDA licensed Zostavax in 2006 to prevent shingles. . Human albumin is a blood plasma protein produced in the liver that, among other functions, transports hormones, fatty acids, and other compounds, and buffers pH. Shingrix provides stronger protection against shingles compared to Zostavax. Visit the VAERS websiteexternal iconor call 1-800-822-7967. While Shingrix is not contraindicated in immunocompromised people, the Advisory Committee on Immunization Practices (ACIP) at this time does not recommend it for this population. Limitations of Use: You can review and change the way we collect information below. Shingrix is safe and effective for most people. Saving Lives, Protecting People, Shingles vaccination is the only way to protect against, National Center for Immunization and Respiratory Diseases, U.S. Department of Health & Human Services. Shingrix is also recommended for adults 19 years and older who have weakened immune systems because of disease or therapy. Viruses can be grown in chicken eggs before being used in vaccinations. CDC uses 3 systems to monitor vaccine safety: English D. Willis, Meredith Woodward, Elizabeth Brown, Zoran Popmihajlov, Patricia Saddier, Paula W. Annunziato, Neal A. Halsey, Anne A. Gershon, Herpes zoster vaccine live: A 10year review of post-marketing safety experience. Accessed February 21, 2023. https://vaccines.procon.org/vaccine-ingredients-and-manufacturer-information/, Born Gay? If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. You will be subject to the destination website's privacy policy when you follow the link. Centers for Disease Control and Prevention. 5 Additionally, Shingrix is not egg-based, and it does not contain thimerosal , a mercury-containing preservative. DTap-IPV (diphtheria, tetanus, pertussis, & polio), 11. Because the two herpes zoster vaccines are different in composition, their potential side effects can differ. Simberkoff MS, Arbeit RD, Johnson GR, Oxman MN, Boardman KD, et al. Shingles is a viral infection caused by herpes zoster, the same virus responsible for chickenpox. It is caused by the varicella-zoster virus (VZV), the same virus that causes chickenpox. Common Ingredients: Medical Research Council 5, human diploid cells (cells containing two sets of chromosomes) derived from the normal lung tissues of a 14-week-old male fetus aborted for "psychiatric reasons" in 1966 in the United Kingdom, Eagle's Basal Medium in Earle's balanced salt solution with bovine serum. yeast protein, amorphous aluminum hydroxyphosphate sulfate, formaldehyde. You will be subject to the destination website's privacy policy when you follow the link. Both Shingrix and Zostavax shingles vaccines have been shown to be safe and well tolerated. Hep A & Hep B Vaccine(hepatitis A & hepatitis B), Hepatitis A Inactivated and Hepatitis B (Recombinant) Vaccine, MRC-5 human diploid cells, formalin, Saccharomyces cerevisiae yeast cells, aluminum salts, listaluminum phosphate, aluminum hydroxide, amino acids, sodium chloride, phosphate buffer, polysorbate 20, water, formalin, MRC-5 cellular proteins, neomycin sulfate, yeast protein, yeast cells, fermentation medium [extract of yeast, soy peptone, dextrose, amino acids, mineral salts], phosphate buffer, formaldehyde, potassium aluminum sulfate, amorphous aluminum hydroxyphosphate sulfate. Protection stays above 85% for at least the first four years after you get vaccinated. The vaccine is also recommended for people who have already gotten another type of shingles vaccine, the live shingles vaccine. CDC recommends two doses of recombinant zoster vaccine (RZV, Shingrix) to prevent shingles and related complications in adults 50 years and older. 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